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The Science Behind Hypnosis Over and over, we hear the question, what is hypnosis and what is the science in it? A brain signature of being hypnotized was first seen in 2012 through functional MRI (fMRI), a kind of MRI showing brain activity with respect to changes in blood flow. Regions of the brain connected with executive control and attention were demonstrated to be involved. In particular, hypnotized subjects exhibited stronger co-activation between components of the executive-control network (manages basic cognitive functions) and the salience network (decides which stimuli should receive attention). In their brains, these two networks reacted together. In those who were not hypnotized, no such connectivity was seen. What elevated these experiments to a higher league is the fact that researchers used fMRI to detect the parts of brain that responded when subjects analyzed colors. The color areas in both left and right hemispheres reacted when the subjects were told to look at colors. The researchers agreed that hypnosis is indeed a one-of-a-kind psychological state and definitely doesn’t come from adopting a role.
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Another newsworthy observation from such experiments were the variations between the hypnotized and non-hypnotized brain. When non-hypnotized subjects were requested to point out colors from a black-and-white picture, only the right hemisphere was activated. Only during hypnosis would the left hemisphere (center of reason and logic) respond.
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Another experiment used positron-emission tomography (PET) to examine cerebral blood flow in hypnosis. The hypnotic state was in relation to activation of many mostly left-sided cortical regions, plus a few right-sided areas. The trend of activation shared a lot of similarities with mental imagery, from which it showed differences by the relative deactivation of the precuneus (handles visuo-spatial imagery, episodic memory retrieval and self-processing operations of the brain). The trend of activation had plenty of similarities with mental imagery, from which it proved different by the relative deactivation of the precuneus, the part of the brain that takes care of the brain’s visuo-spatial imagery, episodic memory retrieval and self-processing operations. For certain scholars, hypnotized subjects simply activate to a large extent, the parts of the brain used in imagination, but don’t cause any real perceptual changes. Another functional MRI study showed limited activity in both anterior cingulate cortex, which affects emotions, learning and memory, and visual areas under hypnosis. The results suggest that hypnosis influences cognitive control by limiting activity in specific brain regions. In multiple studies, hypnotizable subjects exhibited substantially more brain activity in the emotion and behavior-affecting anterior cingulate gyrus, as compared to participants who are non-hypnotized. The anterior cingulate gyrus reacts errors and assesses emotional results. Prefrontal cortex is linked to higher level cognitive processing and behavior. Comparison of findings from several studies also puts contradictory results to fore. Many sections of the brain seem to be activated in different studies. This may be connected to various experimental techniques, both when it comes to equipment and hypnotic approach used by experimenters.